Data and outcome in FunCoup

Release 2.0 (September 2011)

Input datasets


PPI*

MEX**

SCL***

PHP****

MIR*

TFB*

PEX**

GIN*

DOM***

H. sapiens

534922

426

19991

11

653655

2578

11261

3563

M. musculus

226844

448

23876

11

616084

217

R. norvegicus

186866

170

13271

11

574067

66

C. familiaris

87

11941

11

489920

G gallus

108

8963

11

374628

D. rerio

190

11658

12

167745

C. intestinalis

400

12

D. melanogaster

72749

298

9036

12

30716

2021

C. elegans

7069

273

10021

12

55661

330

S. cerevisiae

230610

930

6293

13

1368

255178

A. thaliana

8215

154

25363

12

1627

*:    distinct pairs;
**:   expression conditions;
***:  distinct genes/domains;
****: genomes used for profiling.

PPI: protein-protein interactions
MEX: mRNA expression
SLC: Sub-cellular co-localization
PHP: Phylogenetic profiles
MIR: miRNA-mRNA targeting
TFB: TF-gene targeting
PEX: protein expression
GIN: Genetic interactions
DOM: domain-domain interactions



Output networks of functional coupling

 

Protein-protein interactions

Co-members in protein complex

Metabolic links

Signaling links

Total

H. sapiens

1019182/11196*

1173869/12374

455096/11213

133248/12073

1410649/15540

2458413/14453**

2189103/15629

1213081/14742

439454/16618

3017205/18640

3843847/16035***

3000592/16992

2074016/17954

899506/19923

4675444/21087

M. musculus

779364/10406

948066/14629

606729/11312

110603/7776

1260018/15499

1912783/13779

1733719/17425

1498299/15558

471254/12982

2746726/18634

3075058/15689

2364116/18895

2419853/17569

1098944/15600

4315860/20147

R. norvegicus

675132/9549

596814/10612

416628/9489

33285/4358

888186/11406

1495845/12696

1268817/13722

974135/13132

158196/8900

1973814/14681

2251904/14526

1903576/15521

1580900/14898

406576/11880

3066419/16425

C. familiaris

-

139988/10399

327405/8157

32895/4553

379060/11754

-

274397/14320

876537/11575

156198/9038

994646/15696

-

409685/16535

1514095/13547

400213/11917

1749034/17550

G. gallus

-

83722/5737

232270/6617

20909/3220

282765/8109

-

137450/8655

585605/9476

104736/6543

675943/11053

-

183400/10663

968734/10764

275383/8605

1134553/12458

D. rerio

-

164912/8182

432928/7596

19341/3221

480160/9319

-

329641/11056

1054252/10070

138971/7678

1183450/11933

-

462775/12397

1689964/11280

455137/9914

1999528/13033

C. intestinalis

-

-

59990/2689

34166/2137

74305/2877

-

-

143461/3673

142075/3513

220831/3989

-

-

231693/4242

284024/4119

397038/4540

D. melanogaster

31728/5325

29371/3613

115136/5052

132128/4572

212289/7525

91813/7989

49621/6734

272058/7256

515603/6528

690556/10614

180168/8663

69725/9070

458706/8617

988820/7711

1276343/11679

C. elegans

70442/4477

121514/6309

214607/5187

191798/4496

345616/7764

256605/6902

253888/10579

498741/6894

638016/6367

966089/11942

518958/7794

387981/12544

794278/8078

1131875/7761

1664577/13459

S. cerevisiae

74129/3461

82714/3808

66552/3257

65165/2890

121867/4103

169855/4591

154741/4619

152437/4292

161226/3730

281962/4970

270751/5110

222375/5008

246060/4732

261169/4220

449522/5354

A. thaliana

-

308721/8261

263475/6523

397942/6284

596291/9394

-

543931/11958

510485/9965

885587/9194

1268487/13017

-

756628/14457

767990/12106

1369644/10831

1943407/15278

     *: at confidence > 0.75
    **: at confidence > 0.25

   ***: at confidence > 0.1

 Counts are given as “No. of links” / “No. of distinct genes”