Data and outcome in FunCoup

Release 1.0 (April 2008)

Input datasets


PPI*

MEX**

SCL***

PHP****

MIR*

TFB*

PEX**

DOM*

H. sapiens

182900

338

6009

8

880000

2578

1400

696

M. musculus

40730

1048

4433

7

813000

217


R. norvegicus

183540

666

1545

7

688000

66


D. rerio

C. intestinalis

D. melanogaster

38710

72

582

7

39000

2021

C. elegans

4520

411

1780

7

71000 

330

S. cerevisiae

173170

456

4420

7

1368

A. thaliana

2400

63

2716

5

1627

*:    distinct pairs reported to interact;
**:   gene expression conditions;
***:  distinct proteins with experimentally established sub-cellular localization;
****: genomes used for profiling.

PPI: protein-protein interactions

MEX: mRNA expression

SLC: Sub-cellular co-localization

PHP: Phylogenetic profiles

MIR: miRNA-mRNA targeting

TFB: TF-gene targeting

PEX: protein expression

DOM: domain-domain interactions



Output networks of functional coupling

 

Protein-protein interactions

Co-members in protein complex

Metabolic links

Signaling links

Total

H. sapiens

67353/6678*

99635/7005

32435/3394

6908/2718

122062/8150

201435/11428**

232460/10469

110571/6040

30321/5818

333127/12871

972738/15888***

1018678/16028

938453/13591

345453/13461

1798903/16824

M. musculus

66253/5721

48431/4081

8400/3007

83466/6334

170957/9146

143570/6673

29352/6430

229005/10247

956874/16403

958910/13872

455981/14041

1671640/17016

R. norvegicus

38266/3748

7485/2779

41170/4541

121448/6668

33987/5785

135639/7949

843602/12716

418106/12513

1070567/13950

D. rerio

C. intestinalis

20421/2160

66453/3422

1816513/5375

D. melanogaster

8333/3705

20682/2271

11028/1887

30917/4574

31018/7435

69887/3942

53752/3677

118522/8404

163395/9166

605006/7019

770806/7046

1119491/10033

C. elegans

20583/3012

24043/3668

45087/3052

37723/2664

77092/5065

74449/4941

73630/6301

164921/5021

155012/4423

287178/7605

604811/8445

443358/13360

1055707/7461

1002579/6764

1900943/13821

S. cerevisiae

20653/1912

23659/2095

10121/1314

7994/1273

31173/2418

53871/3817

47318/3022

29009/2127

25031/2098

77229/4191

228696/5315

176875/4679

164505/3873

184178/3465

400617/5463

A. thaliana

11830/2751

13868/2826

23483/3918

39901/5795

64151/5180

94285/6933

369163/11121

544778/9280

813439/11266

     *: at confidence > 0.75
    **: at confidence > 0.25

   ***: at confidence > 0.02

 Counts are given as “No. of links” / “No. of distinct genes”